Fantasy Football Rule #1: Start your studs.
But sometimes you can't. Below is a look at some of the deeper players (many of whom may be on your waiver wire) who may have a great week based on the match-up. Call it informed speculation.
QB Alex Smith @ PHI: Great match-up against one of the worst pass defences in the league. In their last 16 games, the Eagles have allowed 34 TDs & had just 7 INTs. Since half-time in Week 1, the opposing quarterback has completed 72% of their passes for 695 yards, 5 TDs and 1 INT against the Eagles. Smith is a low QB1/high-QB2 with upside this week. This is also great news for Dwayne Bowe.
RB Joique Bell @ WAS: Bush is nursing an injured knee and may not go. Even if he does, I love Bell this week against a Washington defence that made James Starks look like a superstar. Bell is a must-start flex or even RB2 this week.
RB Bilal Powell vs. BUF: This would be a desperation Flex play, but Powell is facing a Bills D that is averaging 140 yrds/gm to opposing RBs (to Vereen and DeAngelo). If you're in injury trouble, he could have a decent day but don't expect 14 points.
WR Kendalll Wright vs SD: Both Chargers games so far this season have turned out to be shoot-outs. Look for Kenny to put up solid WR2 numbers with upside against a porous San Diego secondary that's averaged 375 passing yards allowed through 2 games. This is also good news for Jake Locker, though I still don't think he's worth a start.
WR Mohamed Sanu vs GB: No question that AJ Green will likely steal the show here, but if you're particularly thin at WR, Sanu has a decent matchup when you consider that the Bengals will likely be playing from behind. The Packers have allowed a whopping 360 yards/game passing. This is more of a desperation flex play.
WR Nate Burleson @ WAS: For the same reasons listed above for Bell. The Redskins D is just terrible. This would be a desperation flex play, but I would consider it if Bush can't go (one less mouth to feed). This is obviously great news for Matthew Stafford too.
TE Charles Clay vs ATL: The Falcons are another team that gets thrown on a lot, and have allowed almost 700 yards passing through 2 games. With Mike Wallace drawing the most attention, look for Brian Hartline and Clay to step up. Clay is a decent low-TE1/high TE2 play.
TE Colby Fleener @SF: Dwayne Allen is out for the season. Fleener will be looked to by Luck to step up, though the match-up against the 49ers is less than savoury.
DST Minnesota Vikings vs CLE: Weeden's banged up, Hoyer will be QB. The Browns O-Line is allowing a ton of sacks.
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